Efficiency of correction of vitamin D deficiency with DeviSol Strong at the preconception stage and during pregnancy

Research objective: to assess the course and consequences of pregnancy in women with vitamin D lack deficit that is adjusted DeviSol Strong at pre-pregnancy preparation or during pregnancy.Materials methods. The study involved 145 aged 18 30 years. Experimental cohort (120 deficiency) was divided into three groups: first group – 40 pregnant women, second 50 patients stage preparation, comparison 6–10 weeks gestation. Control consisted 25 sufficient levels D. 25(OH)D value serum determined by immunochemical method chemiluminescent detection. dietary supplement chosen correct deficiency. It administered differently, based on level.Results. Patients receiving 800 IU/day cholecalciferol showed an increase deficiency (from 46.7% 76.7%). Vitamin reduced from 75.0% 32.5% who received 2000 IU 4000 for 3 months, proportion severe decreased 2,4 times. A rapid positive effect achieved 82.0% 6000 (4000 + IU).Abortion risk before 12 gestation occurred 23.3% group, 7.5% 1, 4.0% control 2.0% 2. Early miscarriage 3,3% group. 13.3% 5.0% 1 2 were hospitalized threat premature birth, birth one patient group.Conclusions. Assessment half differentiated correction indicates need supplementation prevention complications. effective drug correcting Most dose IU), deficiency, which allowed achieving adequate level after months 82% patients.